After a decade of stories, and 130 issues of fun Spider-Girl is finally going to get canceled. This is definitely sad news, since Spider-Girl (and later, Amazing Spider-Girl) has been one of the most consistently entertaining books out there. Oh well. All good things must come to an end.
The good news is that we were treated to an awesome Spider-Girl card way back during Marvel Legends. It seems highly unlikely that we’d be so lucky, but seeing some MC2 love during a future Hobby League expansion might be extremely cool.
Besides, nobody is ever really dead in comics. Give it a few years and May Parker will probably end up on another Exiles reboot or something.